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A dog is a man's best friend. You do everything you can to maintain your optimum health. Doesn't your best friend deserve the same? Your dog is an active (probably the most act

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ive!) member of your family and needs the same, if not more attention to health and nutrition as you do, to stay healthy and live longer.

Feeding your dog correctly doesn't ne

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ed to be a full time job for you. All you need to do is use a little commonsense and have correct information about the breed and age of your dog.

Let's divide dogs into two c

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ategories - small & adult.

Small Dogs & Puppies

It has long been established and proven that small dogs have a different metabolism in comparison to large dogs, due to the ph

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

siological effect of their body mass. For example, areat Dane weighing 100 pounds needs to consume about 23 calories per pound of body weight. A Pomeranian weighing 6 pounds

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

needs to consume 47 calories per pound of body weight every day - more than twice as much!

As the owner of a small dog, you need to be certain that your dog's energy needs are

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

being satisfied. Be sure to choose a diet that's been formulated properly with an optimal balance of highly digestible nutrients. Digestibility determines how much your dog c

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n actually utilize of each nutrient in a diet.

Puppies require almost twice or thrice as much food as adult dogs per pound of weight. To keep up their energy levels, they have

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to be fed as frequently as three to four times a day until they are six months of age.

Diet is always the key to raising your puppies. The diet should be balanced, nutrient r

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ich, should contain high levels of phosphorous and calcium and be highly digestible. It should also contain high-quality proteins and should adhere to the Association of Americ

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n Feed Control Officials' (AFFCO) procedures. This ensures that the puppy develops strong bones, muscle and tissue.

For Adult Dogs

Your dog needs a combination of fats, carbo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hydrates, proteins, vitamins, minerals, and water in a balanced diet to meet their daily needs. A lot of dog food bags claim they are a complete food. This means nothing if the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nutrients cannot be absorbed by your dog's system. Major companies take great care in this respect by trying to provide the nutrients in an absorbable form.

Dog foods must al

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

so consist of mineral and vitamin supplements in a balanced form. The proportions should be accurate so that they do not interfere with each other in your dog's system. This pr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

vides the maximum benefit to you dog. If the food consists of one ingredient in overdose and the other in a lower dose, it could have an adverse affect on your dog's health.

G

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

iven below are some feeding tips to make chow time more pleasant:

- Always keep the food dish clean.

- Feed adult dogs twice a day to prevent hogging at one single meal. Thi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s also lessens the chance of your deep chested dog developing bloat or stomach torsion.

- Feeding Schedule should be relaxed so that your dog knows the approximate meal time b

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

t will not bother you if you are a little late.

- Keep people and other pets away from your dog while feeding, so that he does not get insecure and feel a need to defend his f

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ood.

- Never let your dog have free access to food, otherwise they have constant activity in their digestive systems.

- Make sure your dog sits to have his food, so there is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

less chance of food spilling all over the floor.

- Never let your dog play with his dish, teach him manners instead.

- Leave the dish for 15 minutes so that he licks it clean

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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