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With a little care, you can keep leather clothing looking its best for

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

years, according to an expert on leater from The Olde Hide House in Act

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

on, Ontario.

- Leather naturally repels water but, for additonal prote

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tion, look for an environmentally friendly repellent product to help pr

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

event absorption of water and body oils. It's best to avoid silicone-ba

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ed repellents which retard leather's ability to "breathe."

- Let wet l

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eather garments dry in well-ventilated areas, away from heat. The leath

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r may stiffen slightly but should soften again after wearing.

- Hang l

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eather coats and jackets on thick or padded hangers to keep the shoulde

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s in shape. Don't load pockets with heavy or bulky items, which could t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ear seams.

- Plastic bags tend to dry out or discolor leather. Use a c

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

otton garment bag for off-season storage, or hang coats as usual, drapi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

g a tea-towel over the shoulders to deter dust.

- Avoid pressure-sensi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

tive labels (the stick-on type)as the gummy residue left behind by thes

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

labels can stain or ruin the finish on leather.

- Professional cleani

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ng is best for stain removal. Some commercial stain removers can be abs

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rbed and leave a mar. Home remedies include gently rubbing at minor sta

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ins with a pencil eraser or rubbing alcohol (these methods work only on

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

finished leather;; test on the inside facing first, to be sure the leat

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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