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Cashmere and pashmina are best washed by hand, on a very protective delicate/wool mach

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ine cycle or professionally dry-cleaned, the latter being the recommended.

To hand wa

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

h:
- Your garment is easily handwashed in cold/lukewarm water using a mild wool

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

detergent such as woolite or a soap free Wool Mix Detergent specially made for delicat

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

items. Slight fulling is called for as the raised nap of your garment is weighed down

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

by water. This is best done with an old style washing board, but be very gentle.

- T

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e item should then be rolled into a towel to press out excess water and then laid flat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

to dry to avoid creases. - Gently stretch your wool garment into its original shape

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nd allow it to airdry completely.

If you wish to give a more plush, soft texture use

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

a very soft brush to tease the raised nap of the fabric (see Fulling below).

To remov

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

creases from a pashmina either steam press or carefully iron with the added protectio

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

of a pressing cloth. However, if it becomes badly wrinkled we advise having your pash

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

mina dry-cleaned so as not to lose the vitality of the fabric. Do not put your pashmin

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

in a tumble dryer.

Beware of soap! If you are unlucky and your cashmere becomes stai

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ned, do not scrub with soap as the alkaline pH value of soap can do permanent fluffed-

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

p damage. This may also discolor ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

al.com/spring-green-pashmina-scarf.html">green cashmere.

Fulling is the process o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

fluffing up your garment to create the raised nap of the fabric. Excessive fulling of

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

delicate fabrics such as cashmere, wool and silk can ruin them, usually by excesive p

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

lling, soaking, scrubbing and general abrasive behaviour of the common washing mashine

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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